A male motorcyclist has died after a collision in Etobicoke overnight, Toronto police confirm.

Police say the motorcyclist was driving at a high speed heading northbound on Kipling Avenue at Jutland Road shortly after midnight when a BMW SUV travelling southbound turned into the motorcycle's path.

The impact caused the bike to burst into flames, police said.

The motorcyclist, who is believed to be in his late 20s, was pronounced dead at the scene and paramedics say two other patients were transported to a trauma centre in stable condition.

The cause of accident is still being investigated.