BALTIMORE -- Caleb Joseph doubled with two outs in the 10th inning and scored on a passed ball by Josh Thole to give the Baltimore Orioles a 4-3 victory over the Toronto Blue Jays on Wednesday night.

The Orioles scored three runs in the first inning, then waited until the 10th to strike again. After Joseph reached against rookie Joe Biagini (0-1), Joey Rickard got an infield hit and Manny Machado walked.

With Adam Jones at the plate, a pitch from Biagini got past Thole and Joseph sprinted home.

Mychal Givens (1-0) worked the 10th for Baltimore.

Josh Donaldson hit his sixth home run and Edwin Encarnacion had two RBIs for the Blue Jays, whose three-game winning streak ended. Toronto stranded 10 and went 2 for 12 with runners in scoring position.

Down 3-2, the Blue Jays pulled even in the seventh. After Jones made a sensational diving catch of a sinking liner to centre by Jose Bautista with Michael Saunders on third base, Encarnacion delivered a two-out double.

Orioles starter Ubaldo Jimenez gave up two runs, five hits and four walks in five nerve-racking innings. The right-hander allowed the leadoff hitter to reach in each inning but limited Toronto to a 1-for-7 performance with runners in scoring position.

Toronto knuckleballer R.A. Dickey overcame a shaky start to limit Baltimore to three runs and five hits over six innings.

Baltimore's first four batters combined for three hits and a walk. The key blow was an RBI double by Machado, who has a hit in all 13 games this season.

Toronto got to 3-1 in the third when Encarnacion bounced a run-scoring single off Machado's glove at third.

Donaldson opened the fifth with a shot to right.

In the Toronto sixth, Ryan Goins was thrown out at the plate by Rickard, who recovered nicely after making a futile dive to catch Josh Thole's two-out single to left.

DOUBLE TROUBLE

Jimenez worked out of jams in the first two innings. With runners at second and third in the first, he snared a line drive and turned a double play. Facing the same situation in the second inning, he struck out Kevin Pillar and Thole.

TRAINER'S ROOM

Blue Jays: Manager John Gibbons said closer Roberto Osuna (broken fingernail) would not be available for more than an inning. The right-hander got four outs Tuesday and said he couldn't throw a slider.

Orioles: LHP Brian Matusz (ribcage) could come off the DL on Saturday, manager Buck Showalter said. RHP Kevin Gausman (shoulder) made a rehab start with Triple-A Norfolk.

UP NEXT

Blue Jays: Marco Estrada (1-1, 2.77 ERA) makes his third start of the season in the series finale.

Orioles: Chris Tillman (1-1, 5.11) pitches for Baltimore, looking to improve on his 4-10 lifetime record against Toronto.