One person is dead and multiple people are injured following a multi-vehicle collision on Highway 401 east of Kingston on Sunday afternoon.

The Ontario Provincial Police said about 30 to 40 passenger vehicles and tractor trailers were involved in the crash that happened on the westbound lanes of Highway 401 between Highway 15 and Montreal Street at around 2:30 p.m.

Paramedics said 16 patients were taken to hospital, three of them with life-threatening injuries. One other person was treated and released at the scene.

People who were stranded have been taken to a warming centre in Kingston, police said.

All westbound lanes of Highway 401 are closed between Joyceville Road and Highway 15.

The vehicles left on the highway will be towed, OPP said. Motorists are asked to call the Frontenac Detachment of the OPP on Monday for details on where their vehicles are taken.

Police said that stretch of the highway is not expected to reopen until Monday morning.

Kingston was under a winter weather travel advisory due to a storm that brought significant snowfall on Sunday afternoon.

- with files from CTV News Ottawa