TORONTO -- A timeline of key events in the case of Bruce McArthur, who is charged with five counts of first-degree murder.

October 2012 - Majeed Kayhan, 58, of Toronto, is reported missing.

November 2012 - Police launch Project Houston to investigate the disappearance of three men from Toronto's gay village, including Kayhan.

April 2014 - Police close Project Houston, saying none of their findings would classify anyone as a suspect of a criminal offence.

August 2015 - Soroush Mahmudi, 50, of Toronto, is reported missing.

May 2016 - July 2017 -- Police believe Dean Lisowick, 47, of no fixed address, was killed by McArthur during this timespan.

April 14, 2017 - Selim Esen, 44, is reported missing from the area of Toronto's Yonge and Bloor streets.

June 26, 2017 - Andrew Kinsman, 49, is reported missing from the area of Parliament and Winchester streets.

August 2017 - Police launch Project Prism to investigate the disappearances of Esen and Kinsman.

September 2017 - Project Prism officers identify Bruce McArthur "as someone to be included or excluded as being involved in the disappearance of Andrew Kinsman."

Dec. 8, 2017 - Police Chief Mark Saunders says the force will review its practices in missing persons investigations. He denies that there is evidence suggesting a serial killer is walking the streets of Toronto.

Jan. 17, 2018 - Police uncover evidence suggesting McArthur was responsible for both Kinsman and Esen's deaths, along with the deaths of other unidentified people.

Jan. 18, 2018 - McArthur is arrested and charged with first-degree murder in the deaths of Esen and Kinsman. Police say McArthur is believed to be responsible for other deaths.

Jan. 19, 2018 - McArthur has his first court appearance.

Jan. 29, 2018 - McArthur is charged with first-degree murder in the deaths of Mahmudi, Kayhan and Lisowick. Police call McArthur an alleged serial killer and say more victims may be identified.