TORONTO -- Kyle Lowry poured in 29 points and the Toronto Raptors overcame 18 turnovers for a 120-105 win over the short-handed Memphis Grizzlies on Wednesday night.

DeMar DeRozan added 24 points and Patrick Patterson had 14 points and 13 rebounds for the Raptors (12-6), who rode a season-best 16 three-pointers en route to their fourth straight win.

Memphis (11-8) has lost two straight. Andrew Harrison led the Grizzlies with 21 points and Marc Gasol added 18 points and eight rebounds.

The Grizzlies played their first game without star point guard Mike Conley, who suffered a back injury against the Charlotte Hornets and will miss 6-to-8 weeks. They were also without Chandler Parsons, Brandan Wright, Zach Randolph, James Ennis III and former Raptors great, Vince Carter, who has a hip injury.

Toronto came out with a flat and sloppy first half and let the Grizzlies control the game. DeRozan led the underwhelming charge out of the gate, scoring just three points while turning the ball over five times, playing the entire first quarter.

His teammates followed suit, combining to cough up the ball 10 times in the half. Lowry kept a relatively clean sheet, offering just one of those turnovers and scoring 14 points on 4-of-7 shooting from the field.

Gasol put his undermanned team on his back, scoring 14 in the half. His newfound three-point touch -- he's shooting 41 per cent on the season -- was on full display, as he made 2-of-3 from deep in the first half, including one that came on a very friendly roll from the Air Canada Centre rim.

Despite the rash of turnovers, the Raptors only trailed by two at the half, 57-55.

Momentum was hard to come by for both teams, but the Raptors managed to generate a little by the end of the third. They took a three-point lead early in the frame on a DeRozan jumper, but their turnover issues continued to burn them.

Toronto lost the ball six more times in the third, but the Grizzlies were even more careless, losing it seven times. DeRozan and the Raptors' bench unit closed out the quarter, building up an 89-82 lead with an unlikely DeRozan three from the elbow highlighting the run.

Memphis hung around into the fourth quarter, with a Gasol tip-in making it a one-point Raptors lead with 9:10 to go. Three-pointers from Patterson and Cory Joseph opened the game up a little and DeMarre Carroll's corner three with 4:07 left gave the Raptors a 12-point lead.

The Raptors host the L.A. Lakers on Friday.