A female has been transported to hospital with life-threatening injuries following a muitl-vehicle collision.

It happened in the westbound collector lanes of Highway 401 west of Renforth Drive at around 8:30 p.m.

The crash involved two cars and a transport truck, police said. The circumstances surrounding the collision were not immediately clear.

A male also suffered non-life-threatening injuries.

All collector lanes have been closed as police continue to investigate.